Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430112 | 0.84 | TSHR (0.55) | TSHRTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL628320 | 0.83 | TSHR (0.55) | TSHRTDP1DNM1ALDH1A1KDM4E | |
| SCHEMBL16259348 | 0.81 | DNM1 (0.59) | TDP1DNM1CA12CA1CA2 | |
| SCHEMBL12092294 | 0.81 | TSHR (0.38) | TSHRTDP1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL12092182 | 0.80 | TSHR (0.47) | TSHRTDP1ALDH1A1KDM4EPKM | |
| SCHEMBL12079632 | 0.80 | TSHR (0.47) | TSHRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3825313 | 0.80 | TSHR (0.61) | TSHRTDP1DNM1ALDH1A1KDM4E | |
| SCHEMBL12092216 | 0.80 | TSHR (0.47) | TSHRTDP1ALDH1A1KDM4EPKM | |
| SCHEMBL28176853 | 0.80 | TSHR (0.47) | TSHRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL10749240 | 0.79 | TSHR (0.53) | TSHRTDP1CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225359-A1 | ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2023-11-23 | — | — | WO | disclosed |