Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430112 | 0.90 | TSHR (0.55) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL27683153 | 0.87 | TSHR (0.58) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL10596595 | 0.86 | TSHR (0.73) | TSHRTDP1ALDH1A1GAADGKA | |
| SCHEMBL10749240 | 0.84 | TSHR (0.53) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL19296598 | 0.83 | TDP1 (0.67) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL11124203 | 0.83 | TSHR (0.49) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| Allyl Butanoate SCHEMBL263508 | 0.82 | — | — | |
| Allyl Butanoate SCHEMBL16372404 | 0.82 | TSHR (0.71) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL12092182 | 0.81 | TSHR (0.47) | TSHRTDP1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL12092216 | 0.81 | TSHR (0.47) | TSHRTDP1SMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952147-B2 | Conjugates, preparation thereof, and therapeutic use thereof | SANOFI (FR) | 2015-02-10 | — | — | US | disclosed |
| US-20120225089-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-09-06 | — | — | US | disclosed |
| US-20090280977-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L (IT) | 2009-11-12 | — | — | US | disclosed |
| EP-1355955-B1 | CATALYST FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2009-08-26 | — | — | EP | disclosed |
| EP-2051999-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008019802-A1 | PROCESS FOR PREPARING CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (DE) | 2008-02-21 | — | — | WO | disclosed |
| US-6906154-B2 | Catalyst for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-06-14 | — | — | US | disclosed |
| EP-1355955-A1 | CATALYST FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.p.A. (IT) | 2003-10-29 | — | — | EP | disclosed |
| US-20030027715-A1 | Catalyst for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A (IT) | 2003-02-06 | — | — | US | disclosed |
| EP-0790260-B1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5476825-A | Consists of magnesium, titanium and halogen compounds, an organoaluminum compound, a reaction product of organoaluminum or organoboron compound with organosilicon compound | SHOWA DENKO K.K. (JP) | 1995-12-19 | — | — | US | disclosed |
| EP-0383346-B1 | Catalyst, process for its preparation and process for polymerization of olefins using this catalyst | SHOWA DENKO KK (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5407883-A | Containing magnesium, titanium, aluminum and silicon compounds including polymeric aluminum and alumoxanes | SHOWA DENKO K.K. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0640624-A1 | Catalyst for polymerization of olefin and process for the preparation of olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0408635-B1 | TRANSESTERIFICATION OF ALKOXYESTERS | EASTMAN KODAK CO (US) | 1994-02-23 | — | — | EP | disclosed |
| EP-0578473-A1 | Catalyst for polymerization of olefin and process for producing olefin polymer | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041403-A | Magnesium, titanium, halogen, ester compound, and organic aluminum compound | SHOWA DENKO K.K. (JP) | 1991-08-20 | — | — | US | disclosed |
| US-5011977-A | Transesterification of alkoxyesters | EASTMAN KODAK COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0383346-A2 | Catalyst, process for its preparation and process for polymerization of olefins using this catalyst | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-08-22 | — | — | EP | disclosed |
| US-4898969-A | Transesterification of alkoxyesters | EASTMAN KODAK COMPANY (US) | 1990-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225089-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | ERG28, CARS1, FOLH1 | TSHR 4077/4885TDP1 3206/4885SMN1; SMN2 2521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.