Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 3/20 | 0.33 |
| ▸ | ADH1A | P07327 | 3/20 | 0.33 |
| ▸ | ADH7 | P40394 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24798449 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL31228430 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL40122 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL25696346 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL27446945 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL31697503 | 0.89 | TSHR (0.43) | SMN1; SMN2ADH1BADH1AADH7PMP22 | |
| SCHEMBL30822384 | 0.84 | EPHX2 (0.40) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL29465552 | 0.84 | CA12 (0.40) | SMN1; SMN2MEN1KMT2AEGLN1 | |
| SCHEMBL17229458 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ABLMPMP22 | |
| SCHEMBL30433408 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ABLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225359-A1 | ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2023-11-23 | — | — | WO | disclosed |