Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 3/20 | 0.33 |
| ▸ | ADH1A | P07327 | 3/20 | 0.33 |
| ▸ | ADH7 | P40394 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 8/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
| ▸ | CBS | P35520 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22782187 | 0.90 | GLP1R (0.42) | EPHX2CYP2C19SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25696346 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL26902111 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL40122 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL27446945 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL24798449 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL31228430 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ADH1BADH1AADH7MEN1 | |
| SCHEMBL27386798 | 0.83 | SMN1; SMN2 (0.38) | EPHX2CYP2C19SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7268276 | 0.83 | SMN1; SMN2 (0.38) | EPHX2CYP2C19SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30233846 | 0.83 | LMNA (0.40) | EPHX2CYP2C19SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836299-A | Novel bifunctional heterocyclic compounds with Bruton tyrosine kinase decomposition via ubiquitin proteasome pathway and uses thereof | 韩国化学研究院 | 2024-04-05 | — | — | CN | disclosed |