Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089915 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18882749 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30433408 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL26689478 | 0.98 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7191311 | 0.98 | LMNA (0.38) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30449392 | 0.90 | FFAR3 (0.39) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30448818 | 0.90 | FFAR3 (0.39) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL22301008 | 0.90 | FFAR3 (0.39) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL22444994 | 0.90 | ALDH1A1 (0.41) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28978087 | 0.90 | FFAR3 (0.39) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322155-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | Sushou M-conj Biotech Co., Ltd (CN) | 2015-11-12 | — | — | US | disclosed |
| US-20150314017-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD (CN) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322155-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | DCLRE1A, AADAC, UACA | SMN1; SMN2 4698/4885MEN1 1621/4885KMT2A 2220/4885 |
| US-20150314017-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | CD74, CD2, EPCAM | SMN1; SMN2 3882/4885MEN1 1221/4885KMT2A 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.