Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26908474 | 0.84 | DRD2 (0.68) | DRD2DRD3 | |
| SCHEMBL26908456 | 0.82 | DRD3 (0.61) | DRD2DRD3HTR2ASLC6A4HTR2C | |
| SCHEMBL29323243 | 0.82 | DRD3 (0.61) | DRD2DRD3HTR2ASLC6A4HTR2C | |
| SCHEMBL30681700 | 0.81 | DRD2 (0.80) | DRD2DRD3 | |
| SCHEMBL2228622 | 0.80 | DRD2 (1.00) | DRD2DRD3 | |
| SCHEMBL29810747 | 0.79 | DRD2 (0.79) | DRD2DRD3 | |
| SCHEMBL2229736 | 0.77 | DRD2 (1.00) | DRD2DRD3HTR2AHTR2C | |
| SCHEMBL2230504 | 0.77 | DRD2 (1.00) | DRD2DRD3HTR2AHTR2C | |
| SCHEMBL29322744 | 0.76 | DRD2 (1.00) | DRD2 | |
| SCHEMBL2229717 | 0.72 | DRD2 (1.00) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124456-A1 | AZA-ERGOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2024-04-18 | — | — | US | disclosed |
| EP-4286384-A1 | AZA-ERGOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2023-12-06 | — | — | EP | disclosed |
| CN-114835709-A | Aza-ergoline derivative and preparation method and application thereof | 上海科技大学 | 2022-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124456-A1 | AZA-ERGOLINE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ERG, CHRNA7, CHRNA5 | DRD2 13/4885DRD3 125/4885HTR2A 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.