Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | HTR2A | P28223 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323202 | 0.89 | DRD3 (0.48) | DRD3HTR2ADRD2HTR2CSLC6A4 | |
| SCHEMBL29323246 | 0.85 | HTR2A (0.49) | DRD3HTR2ADRD2HTR2CSLC6A4 | |
| SCHEMBL26908456 | 0.82 | DRD3 (0.61) | DRD3HTR2ADRD2HTR2CSLC6A4 | |
| SCHEMBL26908473 | 0.82 | DRD2 (0.66) | DRD3HTR2ADRD2HTR2CSLC6A4 | |
| SCHEMBL30179301 | 0.82 | DRD2 (0.44) | DRD3DRD2 | |
| SCHEMBL28967717 | 0.82 | DRD2 (0.44) | DRD3DRD2 | |
| SCHEMBL29325534 | 0.81 | DRD3 (0.41) | DRD3HTR2ADRD2SLC6A4HTR1A | |
| SCHEMBL29322785 | 0.80 | DRD2 (0.48) | DRD3DRD2HTR1A | |
| SCHEMBL30179173 | 0.80 | DRD2 (0.48) | DRD3DRD2HTR1A | |
| SCHEMBL29324093 | 0.79 | DRD2 (0.50) | DRD3DRD2HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383913-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2024-11-21 | — | — | US | disclosed |
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |
| CN-115772175-A | Thieno-ring compounds, process for their preparation and their use | 中国科学院分子细胞科学卓越创新中心 | 2023-03-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383913-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | TACR1, HTR1F, TPH1 | DRD3 198/4885HTR2A 61/4885DRD2 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.