Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446347 | 1.00 | BTK (0.49) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL30704741 | 0.93 | BTK (0.50) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL26912332 | 0.93 | BTK (0.50) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL26911512 | 0.90 | BTK (0.48) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL30446349 | 0.90 | BTK (0.48) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL26911085 | 0.89 | BTK (0.61) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL30446277 | 0.89 | BTK (0.61) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL30446340 | 0.88 | BTK (0.51) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL26911322 | 0.88 | BTK (0.51) | BTKPTGER1TGM2NPSR1KDM4E | |
| SCHEMBL30446247 | 0.88 | BTK (0.46) | BTKPTGER1TGM2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-12-07 | — | — | US | claimed |
| CN-115956080-A | Bicyclic compounds, compositions containing them and their use | 贝达药业股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-12-07 | — | — | US | disclosed |
| CN-115956080-A | Bicyclic compounds, compositions containing them and their use | 贝达药业股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | CYP11B2, CYP11B1, CYP27A1 | BTK 2459/4885PTGER1 431/4885TGM2 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.