Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 4/20 | 0.48 |
| ▸ | AXL | P30530 | 3/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.48 |
| ▸ | CCR6 | P51684 | 7/20 | 0.45 |
| ▸ | IKBKB | O14920 | 4/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26918826 | 1.00 | MERTK (0.48) | MERTKAXLTYRO3CCR6IKBKB | |
| SCHEMBL29763106 | 0.89 | CCR6 (0.49) | MERTKAXLTYRO3CCR6CCNA2 | |
| SCHEMBL26919457 | 0.89 | CCR6 (0.49) | MERTKAXLTYRO3CCR6CCNA2 | |
| SCHEMBL26918994 | 0.87 | CDK2 (0.58) | MERTKAXLTYRO3CCR6IKBKB | |
| SCHEMBL26918998 | 0.87 | CDK2 (0.58) | MERTKAXLTYRO3CCR6IKBKB | |
| SCHEMBL26942878 | 0.87 | CCR6 (0.47) | MERTKAXLTYRO3CCR6IKBKB | |
| SCHEMBL29763075 | 0.87 | CDK2 (0.58) | MERTKAXLTYRO3CCR6IKBKB | |
| SCHEMBL26942776 | 0.87 | CDK2 (0.58) | MERTKAXLTYRO3CCR6IKBKB | |
| SCHEMBL26942022 | 0.85 | CDK2 (0.47) | MERTKAXLTYRO3LRRK2CCNA2 | |
| SCHEMBL26942034 | 0.85 | CDK2 (0.47) | MERTKAXLTYRO3LRRK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RESEARCH AND DEVELOPMENT CENTRE LTD. (CN) | 2025-01-09 | — | — | US | disclosed |
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | CDK9, CDKL1, CDK6 | MERTK 3148/4885AXL 1284/4885TYRO3 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.