Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.58 |
| ▸ | CCNK | O75909 | 2/20 | 0.58 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.58 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 4/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | CCND3 | P30281 | 2/20 | 0.46 |
| ▸ | CDK7 | P50613 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | CCNH | P51946 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763075 | 1.00 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12IKBKB | |
| SCHEMBL26918994 | 1.00 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12IKBKB | |
| SCHEMBL26942776 | 1.00 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12IKBKB | |
| SCHEMBL26942022 | 0.91 | CDK2 (0.47) | CDK2CCNA2CCNKCDK12CDK1 | |
| SCHEMBL26942034 | 0.91 | CDK2 (0.47) | CDK2CCNA2CCNKCDK12CDK1 | |
| SCHEMBL26942059 | 0.90 | CDK2 (0.63) | CDK2CCNA2CCNKCDK12IKBKB | |
| SCHEMBL26918826 | 0.87 | MERTK (0.48) | CDK2CCNA2CCNKCDK12IKBKB | |
| SCHEMBL26918832 | 0.87 | MERTK (0.48) | CDK2CCNA2CCNKCDK12IKBKB | |
| SCHEMBL26942493 | 0.87 | LRRK2 (0.51) | CDK2CCNA2CCNKCDK12IKBKB | |
| SCHEMBL26942570 | 0.86 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RESEARCH AND DEVELOPMENT CENTRE LTD. (CN) | 2025-01-09 | — | — | US | disclosed |
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| CN-116472270-A | CDK inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-07-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | CDK9, CDKL1, CDK6 | CDK2 11/4885CCNA2 36/4885CCNK 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.