Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dl-Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL638657 | 0.94 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL1007041 | 0.94 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28912532 | 0.91 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL584583 | 0.91 | SLC7A5 (0.42) | SLC7A5ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL21331899 | 0.91 | SLC7A5 (0.42) | SLC7A5ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL584582 | 0.91 | SLC7A5 (0.42) | SLC7A5ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL19209935 | 0.91 | SLC7A5 (0.42) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL27792454 | 0.90 | SLC7A5 (0.57) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28558704 | 0.89 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL8904329 | 0.89 | SLC7A5 (0.56) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288397-A1 | AMINO ACID FERTILIZER, FEED, AND SOIL AMENDMENT MADE FROM BLOOD AND FEATHERS | Aminorganix, Corp. (US) | 2023-12-13 | — | — | EP | disclosed |