SCHEMBL26926331

SCHEMBL26926331

Cc1cc(C(=O)O)cc(C)c1OCCNC(=O)OCc1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.77
LMNA P02545 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MAPT P10636 1/20 0.58
HTT P42858 1/20 0.50
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SLC1A3 P43003 1/20 0.46
SLC1A1 P43005 1/20 0.46
TGM2 P21980 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KEAP1 Q14145 2/20 0.44
NFE2L2 Q16236 2/20 0.44
HTR1A P08908 1/20 0.43
ADRA1D P25100 1/20 0.43
ADRA1A P35348 1/20 0.43
ADRA1B P35368 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4842375 0.91 L3MBTL1 (0.74) L3MBTL1LMNASMN1; SMN2MAPTHTT
SCHEMBL20758227 0.84 L3MBTL1 (0.65) L3MBTL1LMNASMN1; SMN2MAPTHTT
SCHEMBL262646 0.80 MEN1 (0.63) LMNAMEN1KMT2A
SCHEMBL20500014 0.80 L3MBTL1 (0.74) L3MBTL1LMNASMN1; SMN2MAPTHTT
SCHEMBL30732719 0.79 L3MBTL1 (0.58) L3MBTL1LMNASMN1; SMN2MAPTHTT
SCHEMBL4841514 0.79 L3MBTL1 (0.61) L3MBTL1LMNASMN1; SMN2MAPTHTT
SCHEMBL29777995 0.79 NR4A2 (0.64) L3MBTL1LMNASMN1; SMN2MAPTHTT
Hydrochloric Acid SCHEMBL16143479 0.79 MEN1 (0.61) LMNAMEN1KMT2A
SCHEMBL3811564 0.77 L3MBTL1 (0.80) L3MBTL1LMNASMN1; SMN2MAPTHTT
SCHEMBL8235454 0.77 CA12 (0.47) L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 US disclosed
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 EP disclosed
WO-2023239906-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2023-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 L3MBTL1 4827/4885LMNA 1117/4885SMN1; SMN2 301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.