SCHEMBL269272

SCHEMBL269272

COC(=O)c1cc(C(=O)OC)cc(-c2ccc3cc(S(=O)(=O)O)ccc3c2)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLAU P00749 6/20 0.52
CA12 O43570 4/20 0.50
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA9 Q16790 4/20 0.50
PLAT P00750 1/20 0.50
CYP11B1 P15538 2/20 0.48
CYP11B2 P19099 2/20 0.48
CA14 Q9ULX7 3/20 0.47
CYP19A1 P11511 1/20 0.45
SNCA P37840 2/20 0.44
POLB P06746 1/20 0.44
PTPN11 Q06124 1/20 0.43
ERN1 O75460 1/20 0.43
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
KDM4E B2RXH2 1/20 0.42
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270676 0.86 CA12 (0.57) PLAUCA12CA1CA2CA9
SCHEMBL29600590 0.80 SLC6A3 (0.60) PLAUCYP11B1CYP11B2CYP19A1PTPN11
SCHEMBL6840904 0.80 SLC6A3 (0.60) PLAUCYP11B1CYP11B2CYP19A1PTPN11
SCHEMBL30084357 0.79 ABL1 (0.58) PLAUSNCAHSD17B1HSD17B2PTGS2
SCHEMBL28335295 0.79 ABL1 (0.58) PLAUSNCAHSD17B1HSD17B2PTGS2
SCHEMBL15009048 0.78 RARB (0.55) PLAUPLATCYP11B1CYP11B2CYP19A1
SCHEMBL29620305 0.76 LCK (0.57) CA12CA1CA2CA9CA14
SCHEMBL124987 0.76 LCK (0.57) CA12CA1CA2CA9CA14
SCHEMBL472700 0.75 USP2 (0.49) CA12CA1CA2CA9CA14
SCHEMBL6430764 0.75 USP2 (0.49) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030236379-A1 Sulfonated polyester-siloxane resin XEROX CORPORATION 2003-12-25 US claimed
US-6664015-B1 Diacid, diol, and carbinol carboxy terminated polydimethylsiloxane comonomers with at least one being a sulfonate salt; paints, toners, protective coatings XEROX CORPORATION 2003-12-16 US claimed
US-5348832-A Toner compositions XEROX CORPORATION (US) 1994-09-20 US claimed
US-12517445-B2 Toner comprising charge control agent XEROX CORPORATION (US) 2026-01-06 US disclosed
US-12429792-B2 Toner comprising charge control agent XEROX CORPORATION (US) 2025-09-30 US disclosed
US-12405547-B2 Toner comprising reactive charge control agent XEROX CORPORATION (US) 2025-09-02 US disclosed
US-12252568-B2 Silicone copolymer surface additive XEROX CORPORATION (US) 2025-03-18 US disclosed
EP-3578371-B1 WATERBORNE CLEAR INK COMPOSITIONS, PROCESS AND PRINTING PROCESS XEROX CORP (US) 2024-07-10 EP disclosed
EP-3578370-B1 AQUEOUS INK COMPOSITION COMPRISING POLYISOPRENE, PROCESS AND PRINTING PROCESS XEROX CORP (US) 2024-07-10 EP disclosed
EP-3578614-B1 SULFONATED POLYESTER INK XEROX CORP (US) 2023-12-13 EP disclosed
US-11815851-B2 Toner compositions and additives XEROX CORPORATION (US) 2023-11-14 US disclosed
US-6818723-B2 REACTION PRODUCT OF AT LEAST ONE ORGANIC DIOL MONOMER, AT LEAST ONE ORGANIC DIACID MONOMER OR AT LEAST ONE DIESTER MONOMER, AT LEAST ONE CARBINOL CARBOXY TERMINATED POLYDIMETHYLSILOXANE, AND AN ION SALT OF SULFONATE XEROX CORPORATION 2004-11-16 US disclosed
EP-1441260-A1 Toner compositions and processes thereof Xerox Corporation (US) 2004-07-28 EP disclosed
US-20040142266-A1 Toner compositions and processes thereof XEROX CORPORATION 2004-07-22 US disclosed
US-20030236379-A1 Sulfonated polyester-siloxane resin XEROX CORPORATION 2003-12-25 US disclosed
US-6664015-B1 Diacid, diol, and carbinol carboxy terminated polydimethylsiloxane comonomers with at least one being a sulfonate salt; paints, toners, protective coatings XEROX CORPORATION 2003-12-16 US disclosed
US-20030211035-A1 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION 2003-11-13 US disclosed
EP-1055971-A1 Toner, developer compositions, process of imaging, polyester and process for preparation of polyester Xerox Corporation (US) 2000-11-29 EP disclosed
US-6017671-A TONER COMPOSITION COMPRISING A POLYESTER RESIN WITH HYDROPHILIC MOIETIES AND HYDROPHOBIC END GROUPS, COLORANT, WAX, CHARGE ADDITIVE, AND SURFACE ADDITIVES; TRIBOELECTRICAL PROPERTIES XEROX CORPORATION (US) 2000-01-25 US disclosed
US-5348832-A Toner compositions XEROX CORPORATION (US) 1994-09-20 US disclosed