⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692805 | 1.00 | — | — | |
| Leucine SCHEMBL4449412 | 0.81 | SLC7A5 (0.95) | — | |
| Leucine SCHEMBL4449410 | 0.81 | SLC7A5 (0.95) | — | |
| Leucine SCHEMBL5546214 | 0.79 | SLC7A5 (0.90) | — | |
| Leucine SCHEMBL5546212 | 0.79 | SLC7A5 (0.90) | — | |
| Leucine SCHEMBL25241602 | 0.78 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL8568060 | 0.78 | SLC7A5 (1.00) | — | |
| D-Leucine SCHEMBL9449950 | 0.78 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL2478164 | 0.78 | SLC7A5 (1.00) | — | |
| Leucine SCHEMBL175940 | 0.78 | SLC7A5 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891511-A | 20 (S) -ginsenoside Rg 2 Amino acid ester derivative, preparation method and application | 吉林大学 | 2023-10-17 | — | — | CN | claimed |
| CN-114380880-A | Fmoc-amino acid modified 20(S) -protopanoxadiol derivative, preparation method and application thereof | 吉林大学 | 2022-04-22 | — | — | CN | claimed |
| US-20240156792-A1 | COMBINATION THERAPY USING AZABICYCLO COMPOUND FOR CANCER | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-05-16 | — | — | US | disclosed |
| US-11918562-B2 | Combination therapy using azabicyclo compound for cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-03-05 | — | — | US | disclosed |
| CN-116891511-A | 20 (S) -ginsenoside Rg 2 Amino acid ester derivative, preparation method and application | 吉林大学 | 2023-10-17 | — | — | CN | disclosed |
| CN-114380880-B | Fmoc-amino acid modified 20 (S) -protopanoxadiol derivative and preparation method and application thereof | 吉林大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115611872-A | Multi-structure-position modified andrographolide derivative and application thereof | 南京工业大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114380880-A | Fmoc-amino acid modified 20(S) -protopanoxadiol derivative, preparation method and application thereof | 吉林大学 | 2022-04-22 | — | — | CN | disclosed |
| US-20220016090-A1 | COMBINATION THERAPY USING AZABICYCLO COMPOUND FOR CANCER | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2022-01-20 | — | — | US | disclosed |
| US-11166943-B2 | Combination therapy using azabicyclo compound for cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-11-09 | — | — | US | disclosed |
| WO-2021024393-A1 | CANCER COMBINATION THERAPY USING AZABICYCLIC COMPOUND AND POLYADENOSINE-5'-DIPHOSPHATE RIBOSE POLYMERASE INHIBITOR | 大鵬薬品工業株式会社 | 2021-02-11 | — | — | WO | disclosed |
| US-4389524-A | Cepham compounds | CIBA-GEIGY CORPORATION (US) | 1983-06-21 | — | — | US | disclosed |
| US-4319027-A | Process for the manufacture of ceohem enol derivatives | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4301278-A | BY HYDROGENATION IN THE PRESENCE OF A CATALYST | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | disclosed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | disclosed |
| US-4256739-A | 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4255328-A | CEPHALOSPORINS | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4147864-A | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4110533-A | PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4073902-A | ANTIMICROBIAL COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1978-02-14 | — | — | US | disclosed |