Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28771185 | 0.81 | ALDH1A1 (0.44) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL6697255 | 0.80 | ALDH1A1 (0.50) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL30443406 | 0.79 | ALDH1A1 (0.54) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL28771501 | 0.78 | ALDH1A1 (0.41) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL20599579 | 0.76 | ALDH1A1 (0.40) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL20600234 | 0.76 | ALDH1A1 (0.40) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL18322356 | 0.76 | ALDH1A1 (0.47) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL22978715 | 0.75 | ALDH1A1 (0.39) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL20599636 | 0.73 | MGAM (0.38) | ALDH1A1POLBHPGDATML3MBTL1 | |
| SCHEMBL29583386 | 0.73 | ALDH1A1 (0.37) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023237049-A1 | DEGRADATION OF IRAK4 BY CONJUGATION OF IRAK4 INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-12-14 | — | — | WO | disclosed |