Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157269 | 0.83 | HPGD (0.56) | ALDH1A1POLBHPGDSMN1; SMN2MEN1 | |
| SCHEMBL11456775 | 0.80 | ALDH1A1 (0.46) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL6062561 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL26110865 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL26929345 | 0.80 | ALDH1A1 (0.42) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27437666 | 0.80 | SOAT1 (0.50) | ALDH1A1POLBHPGDSMN1; SMN2HTT | |
| SCHEMBL12538260 | 0.78 | ALDH1A1 (0.45) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL14893342 | 0.77 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL28195034 | 0.77 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDHSD11B1SMN1; SMN2 | |
| SCHEMBL1421402 | 0.77 | KMT2A (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167163-A1 | Optically pure paroxetine precursors | ASTUR-PHARMA, S.A. (ES) | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167163-A1 | Optically pure paroxetine precursors | CYP3A5, TPH2, MAOA | ALDH1A1 206/4885POLB 628/4885HPGD 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.