Biphenyl

Biphenyl

SCHEMBL2693002

O=CO.O=CO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
TP53 P04637 1/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP2A6 P11509 1/20 0.45
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
ABCC4 O15439 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44
PTGS1 P23219 1/20 0.44
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MGLL Q99685 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL314914 1.00 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1TP53MAPT
Biphenyl SCHEMBL27698139 1.00 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1TP53MAPT
Biphenyl SCHEMBL4299571 1.00 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1TP53MAPT
Biphenyl SCHEMBL30883064 1.00 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1TP53MAPT
Biphenyl SCHEMBL28815068 0.97 ALDH1A1 (0.56) ALDH1A1MMP3BCL2L1TP53MAPT
Formic Acid SCHEMBL27890706 0.89 KMO (0.58) ALDH1A1MGLLCYP3A4KMO
Benzene SCHEMBL28231912 0.85 ALDH1A1 (0.52) ALDH1A1BCL2L1SMN1; SMN2CYP2A6MAPK1
Formic Acid SCHEMBL27623694 0.85 ALDH1A1 (0.52) ALDH1A1BCL2L1SMN1; SMN2CYP2A6MAPK1
Formic Acid SCHEMBL28296906 0.85 ALDH1A1 (0.52) ALDH1A1BCL2L1SMN1; SMN2CYP2A6MAPK1
Formic Acid SCHEMBL28332944 0.84 NOTUM (0.71) ALDH1A1MAPTSMN1; SMN2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5503762-A OIL ADDITIVES CONTAINING MIXTURES OF ESTERS FROM ALIPHATIC POLYOLS AND MONO- OR DICARBOXYLIC ACIDS WITH ADIPIC ACID ESTERS OF ALIPHATIC MONOHYDRIC ALCOHOLS, FOR HYDRAULIC, COMPRESSOR OR MOTOR OILS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-04-02 US claimed
EP-3187529-B1 THERMOPLASTIC RESIN COMPOSITION AND PRODUCT FORMED THEREFROM CHI MEI CORP (TW) 2018-09-26 EP disclosed
US-8168571-B2 Lubricant combinations EMERY OLEOCHEMICALS GMBH (DE) 2012-05-01 US disclosed
US-20080051303-A1 USE OF POLYETHYLENE GLYCOL ESTERS OF FATTY ACIDS AS LUBRICANTS FOR PLASTICS COGNIS OLEOCHEMICALS GMBH (DE) 2008-02-28 US disclosed
US-20070298986-A1 Lubricant Combinations BANK OF AMERICA, N.A., AS THE ADMINISTRATIVE AGENT 2007-12-27 US disclosed
WO-1998030626-A1 POLYVINYLCHLORIDE PROCESSING AND COMPOSITIONS LINDNER ROBERT A (US) 1998-07-16 WO disclosed
US-5721294-A BLEND OF CORE, SHELL POLYMER AND ANOTHER POLYMER AKZO NOBEL NV (NL) 1998-02-24 US disclosed
US-5716439-A FOR POLYURETHANES BASF CORPORATION (US) 1998-02-10 US disclosed
US-5700390-A CONTAINING POLYMERIC DIMETHYLSILOXANE COMPOUND, DIESTER COMPRISING REACTION PRODUCT OF AROMATIC DICARBOXYLIC ACID AND MONOFUNCTIONAL ALCOHOL BASF CORPORATION (US) 1997-12-23 US disclosed
US-5700869-A CONTAINING INTERNAL MOLD RELEASE COMPOSITION COMPRISING POLYSILOXANE, AROMATIC DIESTER BASF CORPORATION (US) 1997-12-23 US disclosed
US-4279800-A High solids pigmented coating composition containing a blend of ester diols and a curing agent AKZO NV (NL) 1981-07-21 US disclosed
US-4271062-A ESTER DIOL BLEND WITH CURING AGENT, PRIMERS, TOP COATS AKZO N.V. (NL) 1981-06-02 US disclosed
US-4242406-A REINFORCING LAYER OF CURABLE POLYESTER OR EPOXY RESIN PPG INDUSTRIES, INC. (US) 1980-12-30 US disclosed
EP-0018051-A1 Pigment-containing coating composition having a high solids content AKZO N.V. (NL) 1980-10-29 EP disclosed
EP-0018052-A1 Pigment-containing coating composition having a high solids content AKZO N.V. (NL) 1980-10-29 EP disclosed
US-4220731-A FROM POLYEPOXIDE COMPOUND AND POLYISOCYANATE CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
EP-0008837-A1 Radiation curable liquid coating composition based on an epoxy terminated compound and a process for coating a substrate with such a composition AKZO N.V. (NL) 1980-03-19 EP disclosed
US-4157990-A Lubricating and anti-tack compositions useful in the shaping of thermoplastics containing mixed esters and esters of C32-72 monoalcohols with C18-72 monoacids HENKEL INC. (US) 1979-06-12 US disclosed
US-3963686-A Heat-curable pulverulent coating agent consisting of a mixture of compounds containing glycidyl groups, dicarboxylic acid anhydrides, curing accelerators, flow control agents and optionally further customary additives HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3931058-A POLYGLYCIDYL COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND USE CIBA-GEIGY AG (CH) 1976-01-06 US disclosed