Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837810 | 0.84 | TRPV1 (0.42) | KDM4APTPN11GAAKCNA5L3MBTL1 | |
| SCHEMBL30683092 | 0.84 | GABRA1 (0.40) | KDM4APTPN11GAANQO2KCNA5 | |
| SCHEMBL30178972 | 0.84 | KDM4A (0.41) | KDM4APTPN11NQO2KCNA5GABRA1 | |
| SCHEMBL24838769 | 0.84 | KDM4A (0.41) | KDM4APTPN11NQO2KCNA5L3MBTL1 | |
| SCHEMBL24837857 | 0.84 | KDM4A (0.41) | KDM4APTPN11NQO2KCNA5GABRA1 | |
| SCHEMBL24838314 | 0.82 | IDO1 (0.46) | KDM4APTPN11GAAKCNA5HSD17B10 | |
| SCHEMBL15729523 | 0.82 | EPHX2 (0.41) | KDM4APTPN11KCNA5GABRA1GABRG2 | |
| SCHEMBL26931949 | 0.81 | AAK1 (0.42) | KDM4AGAANQO2KCNA5ALDH1A1 | |
| SCHEMBL30178894 | 0.81 | CA12 (0.37) | KDM4APTPN11KCNA5L3MBTL1GABRA1 | |
| SCHEMBL24837853 | 0.81 | CA12 (0.37) | KDM4APTPN11KCNA5L3MBTL1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |