Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837814 | 0.86 | TRPV1 (0.42) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL30178965 | 0.85 | GABRA1 (0.42) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL24837858 | 0.85 | GABRA1 (0.42) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL24838771 | 0.85 | GABRA1 (0.42) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL24838313 | 0.84 | IDO1 (0.43) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL15729791 | 0.84 | GABRA1 (0.41) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL26931830 | 0.84 | GABRA1 (0.41) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL1476738 | 0.84 | GABRA1 (0.41) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL26931908 | 0.84 | KDM4A (0.39) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL26932026 | 0.81 | GABRA5 (0.39) | GABRA1GABRA5GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |