Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074739 | 0.96 | LMNA (0.60) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL26931897 | 0.86 | KDM4E (0.59) | LMNAKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL19668774 | 0.84 | KDM4E (0.61) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL26932213 | 0.82 | LMNA (0.44) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL21074713 | 0.82 | LMNA (0.67) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL19668798 | 0.82 | KDM4E (0.61) | LMNAKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL19668802 | 0.80 | KDM4E (0.66) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL21074774 | 0.80 | LMNA (0.69) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL26935202 | 0.79 | LMNA (0.45) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL19668425 | 0.78 | KDM4E (0.59) | LMNAKMT2AKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2023-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BPGM, PHPT1, NQO2 | LMNA 2774/4885KMT2A 4250/4885MEN1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.