Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | IL33 | O95760 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359712 | 0.83 | ALDH1A1 (0.38) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL22288355 | 0.83 | ALDH1A1 (0.38) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL26934110 | 0.83 | TYK2 (0.33) | ALDH1A1CYP2C19TYK2JAK2 | |
| SCHEMBL20225765 | 0.82 | MAPT (0.37) | MAPTCHEK1NPC1ALDH1A1MEN1 | |
| SCHEMBL30536159 | 0.81 | NPC1 (0.34) | MAPTNPC1ALDH1A1S1PR1CYP1A2 | |
| SCHEMBL30660738 | 0.76 | TYK2 (0.35) | MAPTNPC1ALDH1A1MEN1S1PR1 | |
| SCHEMBL29607458 | 0.75 | TYK2 (0.42) | TYK2JAK2 | |
| SCHEMBL15690274 | 0.75 | TYK2 (0.42) | TYK2JAK2 | |
| SCHEMBL26931418 | 0.74 | RAB9A (0.37) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL2145172 | 0.73 | CYP1A2 (0.40) | MAPTNPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4538269-A1 | SUBSTITUTED PYRIDAZINE-3-CARBOXAMIDE COMPOUND SERVING AS TYK2 INHIBITOR | Guangzhou Fermion Technology Co., Ltd. (CN) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023236947-A1 | SUBSTITUTED PYRIDAZINE-3-CARBOXAMIDE COMPOUND SERVING AS TYK2 INHIBITOR | 广州费米子科技有限责任公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-117186075-A | Substituted pyridazine-3-carboxamide compounds as TYK2 inhibitors | 广州费米子科技有限责任公司 | 2023-12-08 | — | — | CN | disclosed |