Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 1.00 |
| ▸ | GAA | P10253 | 11/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MITF | O75030 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 12/20 | 0.72 |
| ▸ | NPC1 | O15118 | 11/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.68 |
| ▸ | RELA | Q04206 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26915332 | 1.00 | MAPT (1.00) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9869669 | 0.87 | MAPT (0.78) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9520088 | 0.87 | MAPT (0.78) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7863738 | 0.82 | MAPT (0.68) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7863736 | 0.82 | MAPT (0.68) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2681914 | 0.82 | RAB9A (0.74) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL714966 | 0.82 | RAB9A (0.74) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL714967 | 0.82 | RAB9A (0.74) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26935005 | 0.80 | MAPT (1.00) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26935013 | 0.80 | GAA (0.72) | MAPTGAASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289422-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kyushu University, National University Corporation (JP) | 2023-12-13 | — | — | EP | disclosed |