Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.78 |
| ▸ | GAA | P10253 | 13/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.78 |
| ▸ | MEN1 | O00255 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | MITF | O75030 | 3/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 14/20 | 0.67 |
| ▸ | NPC1 | O15118 | 13/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520088 | 1.00 | MAPT (0.78) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26915332 | 0.87 | MAPT (1.00) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26935010 | 0.87 | MAPT (1.00) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9520101 | 0.86 | MAPT (0.59) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9869681 | 0.86 | MAPT (0.59) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2681914 | 0.77 | RAB9A (0.74) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL714966 | 0.74 | RAB9A (0.74) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL714967 | 0.74 | RAB9A (0.74) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26915270 | 0.73 | GAA (0.72) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26915313 | 0.73 | MAPT (1.00) | MAPTGAASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072042-A | Skin disorders, anticarcinogenic-antitumor agent | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |