SCHEMBL26936005

SCHEMBL26936005

C=CC(=O)OCc1ccc2cc3ccccc3cc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.46
TGM2 P21980 2/20 0.46
RAB9A P51151 1/20 0.43
F13A1 P00488 1/20 0.43
TGM1 P22735 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
EGFR P00533 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
JAK1 P23458 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15020200 1.00 THRB (0.46) THRBTGM2RAB9AF13A1TGM1
SCHEMBL15020010 1.00 THRB (0.46) THRBTGM2RAB9AF13A1TGM1
SCHEMBL30715271 0.95 TGM2 (0.49) THRBTGM2RAB9AF13A1TGM1
SCHEMBL845505 0.95 TGM2 (0.49) THRBTGM2RAB9AF13A1TGM1
SCHEMBL16125664 0.92 THRB (0.49) THRBTGM2RAB9AF13A1TGM1
SCHEMBL26936006 0.87 AKR1B1 (0.47) THRBTGM2RAB9AF13A1TGM1
SCHEMBL22722216 0.87 THRB (0.51) THRBTGM2RAB9AF13A1TGM1
SCHEMBL13171589 0.84 THRB (0.41) THRBTGM2F13A1TGM1ALDH1A1
SCHEMBL17791315 0.83 THRB (0.51) THRBTGM2RAB9AKDM4EALDH1A1
SCHEMBL16709779 0.82 THRB (0.42) THRBTGM2RAB9AF13A1TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289877-A1 NOVEL COPOLYMER KOWA COMPANY, LTD. (JP) 2023-12-13 EP disclosed
CN-115989251-A Composition comprising an additive having polycyclic aromatic groups 伊英克公司 2023-04-18 CN disclosed