Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008296 | 0.81 | KDM4E (0.49) | ALDH1A1KDM4EL3MBTL3RORCEED | |
| SCHEMBL15652842 | 0.81 | MAPT (0.50) | ALDH1A1KDM4EL3MBTL3RORCEED | |
| SCHEMBL30389275 | 0.81 | KDM4E (0.40) | ALDH1A1KDM4EADRB1GPR119L3MBTL3 | |
| SCHEMBL3442725 | 0.81 | KDM4E (0.56) | ALDH1A1KDM4EADRB1GPR119L3MBTL3 | |
| SCHEMBL22854286 | 0.81 | HRH3 (0.46) | ALDH1A1KDM4EL3MBTL3RORCEED | |
| Hydrochloric Acid SCHEMBL8591798 | 0.78 | ADRB1 (0.53) | ALDH1A1KDM4EADRB1GPR119MEN1 | |
| SCHEMBL785111 | 0.78 | CHKA (0.53) | ALDH1A1KDM4EL3MBTL3RORCEED | |
| SCHEMBL20494695 | 0.77 | KDM4E (0.53) | ALDH1A1KDM4EL3MBTL3EEDMEN1 | |
| SCHEMBL21542324 | 0.77 | NOTUM (0.50) | ALDH1A1KDM4EGPR119L3MBTL3AKR1C3 | |
| SCHEMBL18693637 | 0.77 | TRIM24 (0.58) | ALDH1A1KDM4EL3MBTL3RORCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137358-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| CN-115677568-B | One-step amination method of p-methylphenol | 南京晓庄学院 | 2024-04-19 | — | — | CN | disclosed |
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| CN-115677568-A | One-step amination method of p-methylphenol | 南京晓庄学院 | 2023-02-03 | — | — | CN | disclosed |