Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.60 |
| ▸ | WNT3A | P56704 | 7/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26940510 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940494 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940499 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940497 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940506 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940500 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940511 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940508 | 1.00 | HPGD (0.72) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940516 | 0.99 | HPGD (0.74) | HPGDALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL26940514 | 0.99 | HPGD (0.74) | HPGDALDH1A1TP53SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230398091-A9 | COMPOUNDS AND METHODS FOR FORMING ION CHANNELS IN BIOLOGICAL MEMBRANES | WASHINGTON UNIVERSITY (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230398091-A9 | COMPOUNDS AND METHODS FOR FORMING ION CHANNELS IN BIOLOGICAL MEMBRANES | WASHINGTON UNIVERSITY (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230398091-A9 | COMPOUNDS AND METHODS FOR FORMING ION CHANNELS IN BIOLOGICAL MEMBRANES | WASHINGTON UNIVERSITY (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230060873-A1 | COMPOUNDS AND METHODS FOR FORMING ION CHANNELS IN BIOLOGICAL MEMBRANES | WASHINGTON UNIVERSITY (US) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230398091-A9 | COMPOUNDS AND METHODS FOR FORMING ION CHANNELS IN BIOLOGICAL MEMBRANES | KCNC1, KCNE1, KCNB1 | HPGD 2445/4885ALDH1A1 3068/4885TP53 4853/4885 |
| US-20230060873-A1 | COMPOUNDS AND METHODS FOR FORMING ION CHANNELS IN BIOLOGICAL MEMBRANES | KCNC1, KCNE1, KCNB1 | HPGD 2445/4885ALDH1A1 3068/4885TP53 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.