Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.46 |
| ▸ | CDK2 | P24941 | 11/20 | 0.46 |
| ▸ | CCND1 | P24385 | 3/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCND3 | P30281 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.46 |
| ▸ | CDK9 | P50750 | 7/20 | 0.46 |
| ▸ | CDK7 | P50613 | 5/20 | 0.46 |
| ▸ | CCNH | P51946 | 5/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | CCNK | O75909 | 6/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 6/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26943497 | 1.00 | ULK1 (0.57) | ULK1CHEK1CCNE1CDK2CCND1 | |
| SCHEMBL26941552 | 0.82 | ULK1 (0.67) | ULK1CCNE1CDK2CCND1CDK6 | |
| SCHEMBL26943494 | 0.80 | ULK1 (0.58) | ULK1CHEK1CCNE1CDK2CCNT1 | |
| SCHEMBL26941950 | 0.76 | CDK2 (0.65) | ULK1CCNE1CDK2CCND1CDK6 | |
| SCHEMBL17547443 | 0.75 | ULK1 (1.00) | ULK1 | |
| SCHEMBL26941973 | 0.75 | CCNE1 (0.65) | ULK1CCNE1CDK2CCND1CDK6 | |
| SCHEMBL22977374 | 0.73 | CCNE1 (0.57) | ULK1CCNE1CDK2CCND1CDK6 | |
| SCHEMBL17547453 | 0.73 | ULK1 (0.88) | ULK1 | |
| SCHEMBL31666635 | 0.70 | CCNK (0.61) | ULK1CHEK1CCNE1CDK2CCNT1 | |
| SCHEMBL31666582 | 0.70 | CCNK (0.61) | ULK1CHEK1CCNE1CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |