Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31647196 | 0.82 | HRH3 (0.42) | DRD3KCNH2HRH3CHRNB2CHRNA4 | |
| SCHEMBL27250767 | 0.78 | DRD3 (0.51) | DRD3KCNH2ELANEP2RX7PIM1 | |
| SCHEMBL14490258 | 0.78 | DRD3 (0.51) | DRD3KCNH2ELANEP2RX7GRM4 | |
| SCHEMBL15448368 | 0.77 | DRD2 (0.55) | DRD3KCNH2HRH3ELANEDRD2 | |
| SCHEMBL27774657 | 0.77 | DRD2 (0.58) | DRD3ELANEPIM1DRD2MEN1 | |
| SCHEMBL4395950 | 0.75 | HRH3 (0.35) | DRD3KCNH2HRH3PIM1DRD2 | |
| SCHEMBL26944374 | 0.74 | OPRM1 (0.43) | DRD3KCNH2ELANEPIM1 | |
| SCHEMBL1727049 | 0.73 | AKR1C3 (0.52) | DRD3KCNH2HRH3NPC1RAB9A | |
| SCHEMBL14490582 | 0.73 | DRD3 (0.44) | DRD3KCNH2ELANEP2RX7DRD2 | |
| SCHEMBL3577171 | 0.73 | MAPT (0.47) | DRD3HRH3DRD2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235925-A1 | COMPOUNDS WITH MERTK ACTIVITY | MONASH UNIVERSITY (AU) | 2023-12-14 | — | — | WO | disclosed |