Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | MARS1 | P56192 | 3/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26944457 | 0.93 | POLRMT (0.33) | POLRMTRIPK1TMPRSS2MARS1 | |
| SCHEMBL24312556 | 0.89 | RIPK1 (0.34) | POLRMTRIPK1TMPRSS2MARS1DOT1L | |
| SCHEMBL25607769 | 0.88 | RIPK1 (0.33) | POLRMTRIPK1TMPRSS2MARS1DOT1L | |
| SCHEMBL26944556 | 0.87 | POLRMT (0.33) | POLRMTRIPK1TMPRSS2DOT1L | |
| SCHEMBL24917062 | 0.87 | POLRMT (0.34) | POLRMTRIPK1TMPRSS2DOT1L | |
| SCHEMBL24312549 | 0.87 | POLRMT (0.35) | POLRMTRIPK1TMPRSS2DOT1L | |
| SCHEMBL24312614 | 0.86 | RIPK1 (0.33) | POLRMTRIPK1TMPRSS2MARS1 | |
| SCHEMBL24312579 | 0.86 | RIPK1 (0.33) | POLRMTRIPK1TMPRSS2MARS1 | |
| SCHEMBL24312633 | 0.86 | TMPRSS2 (0.46) | POLRMTRIPK1TMPRSS2MARS1 | |
| SCHEMBL26149007 | 0.86 | RIPK1 (0.30) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239665-A1 | METHODS FOR TREATMENT OF VIRAL INFECTIONS INCLUDING SARS-COV-2 | GILEAD SCIENCES, INC. (US) | 2023-12-14 | — | — | WO | disclosed |