Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 6/20 | 0.46 |
| ▸ | AXL | P30530 | 13/20 | 0.44 |
| ▸ | MERTK | Q12866 | 13/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18860989 | 0.87 | FYN (0.55) | FYNAXLMERTKCHEK1CHEK2 | |
| SCHEMBL18861171 | 0.80 | FYN (0.46) | FYNAXLMERTKCHEK1CHEK2 | |
| SCHEMBL18860959 | 0.78 | CHEK2 (0.52) | FYNAXLMERTKCHEK1CHEK2 | |
| SCHEMBL19048389 | 0.76 | CHEK1 (0.53) | FYNAXLMERTKCHEK1CHEK2 | |
| SCHEMBL29631737 | 0.75 | FYN (0.60) | FYNCHEK1CHEK2 | |
| SCHEMBL15334326 | 0.75 | FYN (0.60) | FYNCHEK1CHEK2 | |
| SCHEMBL18860437 | 0.74 | FYN (0.69) | FYNCHEK1CHEK2 | |
| SCHEMBL18861106 | 0.71 | FYN (0.61) | FYNCHEK1CHEK2 | |
| SCHEMBL18861126 | 0.71 | CHEK2 (0.52) | FYNAXLMERTKCHEK1CHEK2 | |
| SCHEMBL29631642 | 0.70 | FYN (0.59) | FYNCHEK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3603638-B1 | COMBINATION THERAPY TECHNIQUE FOR AXL INHIBITORY AGENT AND EGFR TYROSINE KINASE INHIBITOR | DAIICHI SANKYO CO LTD (JP) | 2023-12-13 | — | — | EP | disclosed |