Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.38 |
| ▸ | ATG7 | O95352 | 9/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26027103 | 0.85 | DOT1L (0.36) | DOT1LPOLRMTRIPK1 | |
| SCHEMBL24606262 | 0.85 | DOT1L (0.36) | DOT1LPOLRMTRIPK1 | |
| SCHEMBL23960103 | 0.83 | DOT1L (0.38) | DOT1LPOLRMTRIPK1 | |
| SCHEMBL27121518 | 0.83 | DOT1L (0.40) | DOT1LATG7POLRMTRIPK1 | |
| SCHEMBL26268832 | 0.83 | DOT1L (0.39) | DOT1LATG7POLRMT | |
| SCHEMBL27121501 | 0.83 | DOT1L (0.40) | DOT1LATG7POLRMT | |
| SCHEMBL26282567 | 0.82 | DOT1L (0.38) | DOT1LATG7POLRMT | |
| SCHEMBL25400732 | 0.82 | DOT1L (0.38) | DOT1LATG7POLRMT | |
| SCHEMBL27121353 | 0.82 | DOT1L (0.34) | DOT1LATG7POLRMT | |
| SCHEMBL24606235 | 0.82 | ADRB1 (0.40) | DOT1LPOLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054618-A1 | METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2023239665-A1 | METHODS FOR TREATMENT OF VIRAL INFECTIONS INCLUDING SARS-COV-2 | GILEAD SCIENCES, INC. (US) | 2023-12-14 | — | — | WO | disclosed |