Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.37 |
| ▸ | POLRMT | O00411 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25008844 | 1.00 | ADRB1 (0.40) | ADRB1DNMT1ADORA3ADORA2ADOT1L | |
| SCHEMBL30560912 | 1.00 | ADRB1 (0.40) | ADRB1DNMT1ADORA3ADORA2ADOT1L | |
| SCHEMBL22972736 | 1.00 | ADRB1 (0.40) | ADRB1DNMT1ADORA3ADORA2ADOT1L | |
| SCHEMBL10154373 | 1.00 | ADRB1 (0.40) | ADRB1DNMT1ADORA3ADORA2ADOT1L | |
| SCHEMBL26268832 | 0.89 | DOT1L (0.39) | DOT1LPOLRMTSTING1ACVRL1 | |
| SCHEMBL19412423 | 0.87 | DOT1L (0.37) | ADRB1DNMT1ADORA3ADORA2ADOT1L | |
| SCHEMBL17114389 | 0.83 | DOT1L (0.33) | DOT1LPOLRMT | |
| SCHEMBL26282567 | 0.82 | DOT1L (0.38) | DOT1LPOLRMT | |
| SCHEMBL25400732 | 0.82 | DOT1L (0.38) | DOT1LPOLRMT | |
| SCHEMBL26946941 | 0.82 | DOT1L (0.38) | DOT1LPOLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022142477-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-07-07 | — | — | WO | disclosed |