Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26329723 | 0.84 | OPRM1 (0.34) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL26948626 | 0.83 | SMN1; SMN2 (0.35) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL26950506 | 0.82 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL23103556 | 0.81 | HRH3 (0.35) | CYP2D6 | |
| SCHEMBL26948630 | 0.81 | HTR4 (0.31) | HTR4CYP2D6 | |
| SCHEMBL23103552 | 0.78 | SMN1; SMN2 (0.45) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL23103551 | 0.77 | POLB (0.42) | HTR4 | |
| SCHEMBL25443835 | 0.76 | HRH3 (0.36) | CYP2D6 | |
| SCHEMBL7849180 | 0.73 | CHRNA7 (0.39) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL408516 | 0.72 | CHRNA7 (0.34) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |