SCHEMBL26948754

SCHEMBL26948754

C=CCn1c(=O)[nH]c2nccnc2c1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 4/20 0.58
ADORA3 P0DMS8 1/20 0.58
KDM4E B2RXH2 3/20 0.48
ADORA1 P30542 1/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
RGS12 O14924 1/20 0.44
USP2 O75604 1/20 0.44
TNNI3 P19429 1/20 0.44
TNNT2 P45379 1/20 0.44
TNNC1 P63316 1/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
LMNA P02545 2/20 0.41
ADORA2A P29274 3/20 0.39
CYP3A4 P08684 2/20 0.37
CHEK1 O14757 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
ADRA1B P35368 1/20 0.36
PDE4A P27815 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9885811 0.75 KDM4E (0.48) ADORA2BADORA3KDM4EADORA1KMT2A
SCHEMBL11554702 0.74 DAO (0.54) ADORA2BADORA3KDM4EKMT2AMEN1
SCHEMBL11873472 0.74 ADORA2B (0.59) ADORA2BADORA3KDM4EADORA1KMT2A
SCHEMBL6464355 0.74 ADORA2B (1.00) ADORA2BADORA3KDM4EADORA1KMT2A
SCHEMBL7154157 0.73 ADORA2B (0.49) ADORA2BADORA3KDM4EADORA1KMT2A
SCHEMBL9302134 0.73 ADORA2B (0.56) ADORA2BADORA3ADORA1ADORA2ACYP3A4
SCHEMBL5134361 0.73 ADORA2B (0.97) ADORA2BADORA3KDM4EADORA1KMT2A
SCHEMBL7020404 0.72 KDM4E (0.45) ADORA2BADORA3KDM4ELMNAADORA2A
SCHEMBL7020408 0.72 KDM4E (0.45) ADORA2BADORA3KDM4ELMNAADORA2A
SCHEMBL4184996 0.72 KDM4E (0.61) KDM4EKMT2AMEN1RGS12USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399423-A1 POLYMERIC DISINFECTANTS AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-12-14 US disclosed
US-20230399423-A1 POLYMERIC DISINFECTANTS AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399423-A1 POLYMERIC DISINFECTANTS AND USES THEREOF CUTA, PRKDC, PIK3C3 ADORA2B 2661/4885ADORA3 2759/4885KDM4E 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.