SCHEMBL26949481

SCHEMBL26949481

c1cc(-c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cc2)c2cc(-c3ccc4cccc(-c5c6ccccc6c(-c6ccc7oc8ccccc8c7c6)c6ccccc56)c4c3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
MAPT P10636 4/20 0.38
HPGD P15428 4/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
ENPP3 O14638 1/20 0.36
ENPP1 P22413 1/20 0.36
ALOX5 P09917 1/20 0.36
PIM1 P11309 1/20 0.36
HSD17B10 Q99714 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26949639 1.00 CA12 (0.39) CA12CA1CA2CA9MAPT
SCHEMBL26949482 0.99 KDM4E (0.39) CA12CA1CA2CA9MAPT
SCHEMBL26949491 0.96 PLA2G2A (0.40) CA12CA1CA2CA9MAPT
SCHEMBL26949400 0.96 MAPT (0.41) MAPTHPGDKDM4EALDH1A1MEN1
SCHEMBL26949484 0.95 CASP3 (0.37) CA12CA1CA2CA9MAPT
SCHEMBL26949641 0.95 KDM4E (0.40) CA12CA1CA2CA9MAPT
SCHEMBL26949401 0.95 KDM4E (0.41) CA12CA1CA9MAPTHPGD
SCHEMBL26949486 0.94 HSP90AA1 (0.35) CA12CA1CA2CA9MAPT
SCHEMBL21169741 0.94 CA12 (0.40) CA12CA1CA2CA9MAPT
SCHEMBL26950312 0.94 CA12 (0.38) CA12CA1CA2CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023239193-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed