Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26952600 | 0.90 | L3MBTL1 (0.49) | L3MBTL1TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL26952628 | 0.90 | L3MBTL1 (0.49) | L3MBTL1TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL18630954 | 0.87 | CA1 (0.49) | TSHRALDH1A1FFAR4 | |
| SCHEMBL5453543 | 0.87 | CA1 (0.49) | TSHRALDH1A1FFAR4 | |
| SCHEMBL15927903 | 0.87 | CA1 (0.49) | TSHRALDH1A1FFAR4 | |
| SCHEMBL23970542 | 0.87 | CA1 (0.49) | TSHRALDH1A1FFAR4 | |
| SCHEMBL23970385 | 0.87 | CA1 (0.49) | TSHRALDH1A1FFAR4 | |
| SCHEMBL15927893 | 0.87 | CA1 (0.49) | TSHRALDH1A1FFAR4 | |
| SCHEMBL5925105 | 0.87 | CA1 (0.49) | TSHRALDH1A1FFAR4 | |
| SCHEMBL17407791 | 0.81 | CPB1 (0.51) | TSHRMAPK1ALDH1A1CYP3A4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399314-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399314-A1 | CD73 INHIBITOR AND USE THEREOF | ENTPD5, ENTPD1, NT5E | L3MBTL1 4691/4885TSHR 2133/4885TDP1 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.