Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692512 | 0.98 | MAOA (0.48) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL4562110 | 0.93 | MAOA (0.46) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL2692663 | 0.93 | MAOA (0.46) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL20348110 | 0.92 | MAOA (0.53) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL13006564 | 0.92 | MAOA (0.43) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL5944270 | 0.92 | MAOA (0.43) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL2692769 | 0.92 | MAOA (0.43) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL5944237 | 0.91 | MAOA (0.44) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL4562385 | 0.91 | MKNK1 (0.41) | MAOAMAOBACHECYP2D6MKNK1 | |
| SCHEMBL2691283 | 0.91 | MAOA (0.42) | MAOAMAOBACHECYP2D6MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| EP-2457912-B1 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO LTD (JP) | 2013-12-04 | — | — | EP | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| EP-2457912-A1 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | Hodogaya Chemical Co., Ltd. (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-2053051-B1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| EP-2053051-B1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2053051-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
| EP-2053051-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | SCO2, PNPO, WEE1 | MAOA 151/4885MAOB 513/4885ACHE 1050/4885 |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | PNPO, SCO2, OR10J3 | MAOA 142/4885MAOB 319/4885ACHE 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.