Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5943867 | 0.98 | MKNK1 (0.40) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL5944225 | 0.93 | MAPT (0.39) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL4561488 | 0.93 | MKNK1 (0.39) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL20348119 | 0.92 | MKNK1 (0.44) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL5944410 | 0.92 | RAB9A (0.42) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL5944391 | 0.91 | MKNK1 (0.38) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL2695285 | 0.91 | MAOA (0.49) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL5943786 | 0.91 | TOP2A (0.38) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL5944313 | 0.90 | MKNK1 (0.38) | MKNK1MKNK2MAOAMAOBACHE | |
| SCHEMBL4561409 | 0.89 | MEN1 (0.40) | MKNK1MKNK2DYRK1AMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722209-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| EP-2457912-A1 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | Hodogaya Chemical Co., Ltd. (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-2053051-B1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168308-B2 | Compound having pyridoindole ring structure having substituted pyridyl group attached thereto, and organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230660-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | SCO2, PNPO, WEE1 | MKNK1 4339/4885MKNK2 4401/4885MAOA 151/4885 |
| US-20120298969-A1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT | PNPO, SCO2, OR10J3 | MKNK1 4440/4885MKNK2 4604/4885MAOA 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.