Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.53 |
| ▸ | SGK1 | O00141 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.49 |
| ▸ | FYN | P06241 | 3/20 | 0.49 |
| ▸ | STK4 | Q13043 | 1/20 | 0.49 |
| ▸ | STK3 | Q13188 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734958 | 1.00 | CDK2 (0.53) | CDK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL31735137 | 0.89 | LRRK2 (0.45) | CDK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL26953219 | 0.89 | LRRK2 (0.45) | CDK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL3768598 | 0.88 | CDK2 (0.55) | CDK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL31735012 | 0.87 | SGK1 (0.57) | CDK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL26953278 | 0.87 | SGK1 (0.57) | CDK2CDC7ROCK2MAP4K4PIM1 | |
| SCHEMBL26953145 | 0.86 | LRRK2 (0.59) | SGK1TAAR1LRRK2FYNSTK4 | |
| SCHEMBL31735005 | 0.86 | LRRK2 (0.59) | CDK2SGK1LRRK2STK4STK3 | |
| SCHEMBL26953170 | 0.86 | LRRK2 (0.59) | CDK2SGK1LRRK2STK4STK3 | |
| SCHEMBL31734890 | 0.86 | LRRK2 (0.59) | SGK1TAAR1LRRK2FYNSTK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |