Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.52 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.52 |
| ▸ | IKBKB | O14920 | 5/20 | 0.50 |
| ▸ | CHUK | O15111 | 5/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734996 | 1.00 | NUDT1 (0.58) | NUDT1AURKBAURKAINCENPTPX2 | |
| SCHEMBL26953368 | 0.81 | PRKCI (0.54) | NUDT1AURKBIKBKBCHUKROCK1 | |
| SCHEMBL1717710 | 0.76 | PRKCI (0.61) | NUDT1AURKBAURKAINCENPTPX2 | |
| SCHEMBL26953081 | 0.74 | PRKCI (0.48) | NUDT1AURKBAURKAINCENPTPX2 | |
| SCHEMBL31734994 | 0.74 | PRKCI (0.48) | NUDT1AURKBAURKAINCENPTPX2 | |
| SCHEMBL4791464 | 0.74 | IKBKB (0.64) | NUDT1AURKBAURKAINCENPTPX2 | |
| SCHEMBL857132 | 0.73 | IKBKB (0.63) | NUDT1AURKBAURKAINCENPTPX2 | |
| SCHEMBL23496993 | 0.73 | TLR8 (0.58) | NUDT1AURKBIKBKBCHUKROCK1 | |
| SCHEMBL856991 | 0.73 | PRKCI (0.57) | NUDT1AURKBIKBKBCHUKROCK1 | |
| SCHEMBL4791235 | 0.72 | NUDT1 (0.64) | NUDT1AURKBAURKAINCENPTPX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |