Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 2/20 | 0.48 |
| ▸ | CCNK | O75909 | 3/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.45 |
| ▸ | CIT | O14578 | 3/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26953081 | 1.00 | PRKCI (0.48) | PRKCICCNKCDK12NUDT1CIT | |
| SCHEMBL26953368 | 0.81 | PRKCI (0.54) | PRKCICCNKCDK12NUDT1CIT | |
| SCHEMBL31734939 | 0.78 | LRRK2 (0.38) | CCNKCDK12AURKBROCK1DAPK3 | |
| SCHEMBL26953079 | 0.78 | LRRK2 (0.38) | CCNKCDK12AURKBROCK1DAPK3 | |
| SCHEMBL31734859 | 0.76 | PRKCI (0.56) | PRKCICCNKCDK12NUDT1CIT | |
| SCHEMBL26953089 | 0.76 | PRKCI (0.56) | PRKCICCNKCDK12NUDT1CIT | |
| SCHEMBL31734996 | 0.74 | NUDT1 (0.58) | PRKCICCNKCDK12NUDT1CIT | |
| SCHEMBL26953277 | 0.74 | NUDT1 (0.58) | PRKCICCNKCDK12NUDT1CIT | |
| SCHEMBL13765435 | 0.72 | NUDT1 (0.58) | PRKCICCNKCDK12NUDT1CIT | |
| SCHEMBL1752655 | 0.72 | PRKCI (0.53) | PRKCICCNKCDK12NUDT1CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361230-A1 | LATS Inhibitors and Uses Thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2025-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361230-A1 | LATS Inhibitors and Uses Thereof | LATS2, LATS1, AKT1S1 | PRKCI 930/4885CCNK 1376/4885CDK12 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.