Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27250757 | 0.85 | ALDH1A1 (0.40) | HRH3ALOX5APALDH1A1KDM4EITGB1 | |
| SCHEMBL27252253 | 0.83 | HRH3 (0.38) | HRH3ALOX5APALDH1A1KDM4EITGB1 | |
| SCHEMBL27446444 | 0.81 | HRH3 (0.37) | HRH3ALOX5APALDH1A1KDM4EITGB1 | |
| SCHEMBL27250753 | 0.79 | CYP1A2 (0.41) | HRH3ALOX5APALDH1A1KDM4EITGB1 | |
| SCHEMBL23941731 | 0.78 | BRD4 (0.41) | HRH3ALOX5APALDH1A1KDM4EBRD4 | |
| SCHEMBL30249117 | 0.78 | BRD4 (0.41) | HRH3ALOX5APALDH1A1KDM4EBRD4 | |
| SCHEMBL22241874 | 0.78 | CYP2A6 (0.43) | HRH3ALOX5APITGB1ITGA4CYP2A6 | |
| SCHEMBL27252068 | 0.78 | MEN1 (0.41) | HRH3ALOX5APITGB1ITGA4CYP2A6 | |
| SCHEMBL29348780 | 0.77 | HRH3 (0.43) | HRH3ALDH1A1KDM4EITGB1ITGA4 | |
| SCHEMBL27446419 | 0.75 | HRH3 (0.38) | HRH3ALOX5APALDH1A1KDM4EITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289833-A1 | TYK2 INHIBITOR COMPOUND CONTAINING BICYCLIC RING | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-12-13 | — | — | EP | disclosed |