Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 9/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23941731 | 1.00 | BRD4 (0.41) | BRD4CREBBPMKNK1MKNK2FEN1 | |
| SCHEMBL27250753 | 0.83 | CYP1A2 (0.41) | ALOX5APKDM4EALDH1A1HRH3SYK | |
| SCHEMBL27252068 | 0.81 | MEN1 (0.41) | ALOX5APHRH3PIK3CDCCKBR | |
| SCHEMBL22241874 | 0.81 | CYP2A6 (0.43) | ALOX5APHRH3SYK | |
| SCHEMBL27446419 | 0.79 | HRH3 (0.38) | BRD4ALOX5APKDM4EALDH1A1HRH3 | |
| SCHEMBL27250757 | 0.79 | ALDH1A1 (0.40) | BRD4ALOX5APKDM4EALDH1A1HRH3 | |
| SCHEMBL26240869 | 0.78 | CHEK1 (0.46) | BRD4KDM4EALDH1A1GAAHRH3 | |
| SCHEMBL27252253 | 0.78 | HRH3 (0.38) | BRD4CREBBPALOX5APKDM4EALDH1A1 | |
| SCHEMBL26953454 | 0.78 | HRH3 (0.38) | BRD4ALOX5APKDM4EALDH1A1HRH3 | |
| SCHEMBL27446444 | 0.75 | HRH3 (0.37) | BRD4ALOX5APKDM4EALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4136073-A1 | SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES | Gossamer Bio Services, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |