Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 6/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 6/20 | 0.33 |
| ▸ | TTBK1 | Q5TCY1 | 4/20 | 0.33 |
| ▸ | TTBK2 | Q6IQ55 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738486 | 1.00 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNQ1TRPA1SCN5A | |
| SCHEMBL26957347 | 0.81 | L3MBTL1 (0.43) | KCNQ3KCNQ2KCNQ1TRPA1SCN5A | |
| SCHEMBL26958875 | 0.78 | DYRK1A (0.35) | LRRK2JAK2JAK3DYRK1AJAK1 | |
| SCHEMBL30824397 | 0.76 | TNF (0.45) | KCNQ3KCNQ2KCNQ1TRPA1SCN5A | |
| SCHEMBL26955849 | 0.76 | TNF (0.45) | KCNQ3KCNQ2KCNQ1TRPA1SCN5A | |
| SCHEMBL30824432 | 0.73 | LRRK2 (0.35) | LRRK2JAK2JAK3JAK1 | |
| SCHEMBL26957527 | 0.73 | TTBK1 (0.41) | KCNQ3KCNQ2KCNQ1TRPA1SCN5A | |
| SCHEMBL26958874 | 0.70 | MKNK1 (0.37) | LRRK2JAK2SGK1CHEK1AURKA | |
| Formic Acid SCHEMBL30738049 | 0.68 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNQ1TRPA1SCN5A | |
| Formic Acid SCHEMBL26928975 | 0.68 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNQ1TRPA1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101531-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2024-03-28 | — | — | US | claimed |
| US-20240101531-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2024-03-28 | — | — | US | disclosed |
| WO-2023239729-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101531-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | KCNA1, KCNB1, KCNB2 | KCNQ3 18/4885KCNQ2 10/4885KCNQ1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.