SCHEMBL269580

SCHEMBL269580

COc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.70
GAA P10253 2/20 0.63
POLB P06746 1/20 0.63
LPAR1 Q92633 1/20 0.58
BRS3 P32247 1/20 0.57
LTB4R2 Q9NPC1 1/20 0.57
HDAC4 P56524 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
USP2 O75604 1/20 0.55
TP53 P04637 1/20 0.55
TUBB4A P04350 1/20 0.55
TUBB P07437 1/20 0.55
TUBA3C P0DPH7 1/20 0.55
TUBA1B P68363 1/20 0.55
TUBA4A P68366 1/20 0.55
TUBB4B P68371 1/20 0.55
TUBB3 Q13509 1/20 0.55
TUBB2A Q13885 1/20 0.55
TUBB8 Q3ZCM7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrole SCHEMBL1260091 0.91 SMN1; SMN2 (0.59) SMN1; SMN2GAAPOLBLPAR1BRS3
SCHEMBL29011848 0.87 GAA (0.60) SMN1; SMN2GAAPOLBLPAR1HDAC4
SCHEMBL30045516 0.87 GAA (0.60) SMN1; SMN2GAAPOLBLPAR1HDAC4
SCHEMBL1515687 0.86 GAA (0.63) SMN1; SMN2GAAPOLBHDAC4HDAC2
SCHEMBL15780703 0.85 KDM4E (0.64) SMN1; SMN2GAAPOLBKDM4ECYP1A2
SCHEMBL13356437 0.85 SMN1; SMN2 (0.62) SMN1; SMN2GAAPOLBLPAR1HDAC4
SCHEMBL2744891 0.85 SMN1; SMN2 (0.59) SMN1; SMN2GAAPOLBLPAR1BRS3
SCHEMBL18759613 0.84 HNF4A (0.63) SMN1; SMN2LTB4R2KDM4ECYP2C9ALDH1A1
SCHEMBL30292805 0.84 HNF4A (0.63) SMN1; SMN2LTB4R2KDM4ECYP2C9ALDH1A1
SCHEMBL6276231 0.84 SLC6A3 (0.71) SMN1; SMN2GAAPOLBHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689849-B1 PERFUME PRECURSOR TAKASAGO PERFUMERY CO LTD (JP) 2025-01-15 EP claimed
US-20220280494-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2022-09-08 US claimed
EP-3207920-B1 USE OF ACTIVE AGENTS FOR INCREASING THE CERAMIDE CONTENT OF THE LIPS, AS A PROTECTION AGENT FOR FRAGILE LIPS OREAL (FR) 2022-08-10 EP claimed
EP-4021406-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2022-07-06 EP claimed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN claimed
EP-3364941-B1 USE OF GLYCOSIDES TO INCREASE HAIR MASS OREAL (FR) 2021-05-19 EP claimed
WO-2021041730-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. (US) 2021-03-04 WO claimed
US-20210000740-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2021-01-07 US claimed
EP-3758701-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2021-01-06 EP claimed
CN-112004538-A Compositions of small molecule therapeutic compounds 德尔宝股份有限公司 2020-11-27 CN claimed
WO-2018057968-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. (US) 2018-03-29 WO claimed
WO-2018057977-A1 STABLE COMPOSITIONS FOR INCRETIN MIMETIC COMPOUNDS DELPOR, INC. (US) 2018-03-29 WO claimed
EP-1345919-B1 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF OREAL (FR) 2013-05-22 EP claimed
EP-2049077-B1 COMPOSITION COMPRISING AT LEAST ONE C-GLYCOSIDE DERIVATIVE AND AT LEAST ONE HYALURONIC ACID AND ITS COSMETIC USE OREAL (FR) 2010-12-01 EP claimed
EP-1875893-B1 Composition combining a C-glycoside derivative with an associative polymer OREAL (FR) 2010-10-20 EP claimed
EP-1427386-B1 PRODUCTS FOR PREVENTING PENETRATION INTO THE SKIN YISSUM RES DEV CO (IL) 2010-10-20 EP claimed
US-7736630-B2 Products for preventing penetration into the skin YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2010-06-15 US claimed
US-6552022-B1 Atherosclerosis in a mammal, pancreatitis, non-insulin dependent diabetes mellitus, coronary heart disease in a lowering serum lipid levels SMITHKLINE BEECHAM CORPORATION 2003-04-22 US claimed
EP-1135378-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS GLAXO GROUP LIMITED (GB) 2001-09-26 EP claimed
WO-2000032582-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 SECRETION INHIBITORS GLAXO GROUP LIMITED (GB) 2000-06-08 WO claimed