Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14785649 | 0.89 | EPHX2 (0.49) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL27266145 | 0.87 | LMNA (0.48) | ADRA1AEPHX2LMNASLC15A2KDM4E | |
| SCHEMBL14785685 | 0.87 | PRMT1 (0.52) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL14785733 | 0.87 | PRMT1 (0.52) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL14785831 | 0.87 | PRMT1 (0.52) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL14785825 | 0.87 | PRMT1 (0.52) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL14785612 | 0.87 | PRMT1 (0.52) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL14785620 | 0.87 | PRMT1 (0.52) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL14785655 | 0.87 | PRMT1 (0.52) | ADRA1AEPHX2PRMT1LMNAKDM4E | |
| SCHEMBL14785792 | 0.85 | EPHX2 (0.45) | ADRA1AEPHX2PRMT1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289857-A1 | DRUG CONJUGATE OF GLUCOCORTICOID RECEPTOR AGONIST, AND APPLICATION THEREOF IN MEDICINE | Shanghai Senhui Medicine Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |