Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KDM5C | P41229 | 4/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26958824 | 0.87 | ADRA1A (0.50) | LMNASLC15A2KDM4EFAAHCNR1 | |
| SCHEMBL14785792 | 0.82 | EPHX2 (0.45) | LMNAECE1PHF8KDM2AKDM4E | |
| SCHEMBL14785649 | 0.82 | EPHX2 (0.49) | LMNAPHF8KDM2AKDM4EKDM5C | |
| SCHEMBL18646009 | 0.81 | LMNA (0.52) | LMNASLC15A2PHF8KDM2AKDM4E | |
| SCHEMBL14785733 | 0.80 | PRMT1 (0.52) | LMNAPHF8KDM2AKDM4EKDM5C | |
| SCHEMBL14785685 | 0.80 | PRMT1 (0.52) | LMNAPHF8KDM2AKDM4EKDM5C | |
| SCHEMBL14785620 | 0.80 | PRMT1 (0.52) | LMNAPHF8KDM2AKDM4EKDM5C | |
| SCHEMBL14785612 | 0.80 | PRMT1 (0.52) | LMNAPHF8KDM2AKDM4EKDM5C | |
| SCHEMBL14785825 | 0.80 | PRMT1 (0.52) | LMNAPHF8KDM2AKDM4EKDM5C | |
| SCHEMBL14785655 | 0.80 | PRMT1 (0.52) | LMNAPHF8KDM2AKDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110905-A1 | ANTI-CEA ANTIBODY DRUG CONJUGATES AND METHODS OF USE | BEIGENE, LTD. (KY) | 2024-05-30 | — | — | WO | disclosed |