⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11247873 | 0.88 | — | — | |
| Sulfamate SCHEMBL14165105 | 0.85 | — | — | |
| Acetamide SCHEMBL28019241 | 0.85 | BLM (0.61) | — | |
| Acetamide SCHEMBL27622549 | 0.85 | BLM (0.61) | — | |
| Acetamide SCHEMBL5320059 | 0.85 | — | — | |
| Sulfamate SCHEMBL6525631 | 0.84 | — | — | |
| Sulfamate SCHEMBL28535861 | 0.81 | CA1 (0.57) | — | |
| Acetamide SCHEMBL27964490 | 0.81 | BLM (0.57) | — | |
| Sulfamate SCHEMBL10800067 | 0.81 | CA1 (0.57) | — | |
| Sulfamate SCHEMBL12501260 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242845-A1 | SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (CoLDR) COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-12-21 | — | — | WO | claimed |
| US-20230406837-A1 | SULFAMATE MODULATORS OF PIN1 ACTIVITY AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2023-12-21 | — | — | US | disclosed |
| WO-2023242845-A1 | SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (CoLDR) COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-12-21 | — | — | WO | disclosed |