Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Acetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL28019241 | 1.00 | BLM (0.61) | — | |
| Acetamide SCHEMBL27964490 | 0.96 | BLM (0.57) | — | |
| Urea SCHEMBL28006959 | 0.88 | LMNA (0.50) | — | |
| Dimethyl Sulfone SCHEMBL21635409 | 0.88 | — | — | |
| Sulfuric Acid SCHEMBL11247873 | 0.88 | — | — | |
| Urea SCHEMBL2959932 | 0.88 | — | — | |
| Sulfuric Acid SCHEMBL27941813 | 0.86 | BLM (0.53) | — | |
| Sulfamate SCHEMBL26965441 | 0.85 | — | — | |
| Acetamide SCHEMBL27622549 | 0.85 | BLM (0.61) | — | |
| Carbamic Acid SCHEMBL15239339 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452983-A1 | SOLID FORMS OF A TYK2 INHIBITOR, METHOD OF PREPARATION, AND USE THEREOF | BeiGene Switzerland GmbH (CH) | 2024-10-30 | — | — | EP | claimed |
| CN-118401526-A | Solid forms of TYK2 inhibitors, methods of preparation and uses thereof | 百济神州有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-117285514-A | Solid forms of HIV capsid inhibitor | 吉利德科学公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117241789-A | Pharmaceutical composition | 南京创特医药科技有限公司 | 2023-12-15 | — | — | CN | claimed |
| WO-2023116822-A1 | SOLID FORMS OF A TYK2 INHIBITOR, METHOD OF PREPARATION, AND USE THEREOF | BEIGENE, LTD. (KY) | 2023-06-29 | — | — | WO | claimed |
| CN-101151019-A | Pharmaceutical formulations of N- [ 5- (aminosulfonyl) -4-methyl-1, 3-thiazol-2-yl ] -N-methyl-2- [ 4- (2-pyridinyl) phenyl ] acetamide | AICURIS GMBH & CO KG (DE) | 2008-03-26 | — | — | CN | claimed |
| EP-1112252-A4 | KAPPA AGONIST COMPOUNDS AND PHARMACEUTICAL FORMULATIONS THEREOF | ADOLOR CORP (US) | 2004-07-14 | — | — | EP | claimed |
| EP-1112252-A1 | KAPPA AGONIST COMPOUNDS AND PHARMACEUTICAL FORMULATIONS THEREOF | Adolor Corporation (US) | 2001-07-04 | — | — | EP | claimed |
| WO-2000014065-A1 | KAPPA AGONIST COMPOUNDS AND PHARMACEUTICAL FORMULATIONS THEREOF | ADOLOR CORPORATION (US) | 2000-03-16 | — | — | WO | claimed |
| EP-4608832-A1 | 2-(4-(2-(7, 8-DIMETHYL-[1,2,4]TRIAZOLO[1,5-A] PYRIDIN-6-YL)-3-ISOPROPYL-1H-INDOL-5-YL)PIPERIDIN-1-YL)ACETAMIDE SALT AND CRYSTALLINE FORMS THEREOF | Bristol-Myers Squibb Company (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2025106462-A1 | 2-(4-(2-(7, 8-DIMETHYL-[1,2,4]TRIAZOLO[1,5-A] PYRIDIN-6-YL)-3-ISOPROPYL-1H-INDOL-5-YL)PIPERIDIN-1-YL)ACETAMIDE SALT AND CRYSTALLINE FORMS THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-4499600-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | Glenmark Life Sciences Limited (IN) | 2025-02-05 | — | — | EP | disclosed |
| EP-4452983-A1 | SOLID FORMS OF A TYK2 INHIBITOR, METHOD OF PREPARATION, AND USE THEREOF | BeiGene Switzerland GmbH (CH) | 2024-10-30 | — | — | EP | disclosed |
| CN-118401526-A | Solid forms of TYK2 inhibitors, methods of preparation and uses thereof | 百济神州有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-1283317-C | Remedies for sepsis | TORAY INDUSTRIES (JP) | 2006-11-08 | — | — | CN | disclosed |
| EP-1112252-A4 | KAPPA AGONIST COMPOUNDS AND PHARMACEUTICAL FORMULATIONS THEREOF | ADOLOR CORP (US) | 2004-07-14 | — | — | EP | disclosed |
| CN-1507356-A | Remedies for sepsis | ������������ʽ���� | 2004-06-23 | — | — | CN | disclosed |
| CN-1433407-A | Bis-aryl sulfones | PHARMACIA & UP JOHN CO (US) | 2003-07-30 | — | — | CN | disclosed |
| EP-1112252-A1 | KAPPA AGONIST COMPOUNDS AND PHARMACEUTICAL FORMULATIONS THEREOF | Adolor Corporation (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000014065-A1 | KAPPA AGONIST COMPOUNDS AND PHARMACEUTICAL FORMULATIONS THEREOF | ADOLOR CORPORATION (US) | 2000-03-16 | — | — | WO | disclosed |