SCHEMBL26965705

SCHEMBL26965705

CNCCc1cn(C)c2cccc(O)c12

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 11/20 0.65
HTR2C P28335 11/20 0.65
HTR2B P41595 8/20 0.65
GPR84 Q9NQS5 1/20 0.40
CDK2 P24941 2/20 0.39
HTR6 P50406 1/20 0.37
NQO2 P16083 1/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
TAAR1 Q96RJ0 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26965676 0.91 HTR2A (0.62) HTR2AHTR2CHTR2BGPR84CDK2
SCHEMBL26965719 0.84 HTR2A (0.52) HTR2AHTR2CHTR2BHTR6TAAR1
SCHEMBL26965667 0.82 HTR2A (0.67) HTR2AHTR2CHTR2BHTR6TAAR1
SCHEMBL26965630 0.81 HTR2C (0.68) HTR2AHTR2CHTR2BGPR84TAAR1
SCHEMBL23819793 0.81 HTR2A (0.56) HTR2AHTR2CHTR2BCDK2HTR6
SCHEMBL23819939 0.81 HTR2A (0.63) HTR2AHTR2CHTR2BCDK2HTR6
SCHEMBL23819789 0.81 HTR2A (0.56) HTR2AHTR2CHTR2BCDK2HTR6
Hydrochloric Acid SCHEMBL23805218 0.80 HTR2A (0.55) HTR2AHTR2CHTR2BCDK2HTR6
Hydrochloric Acid SCHEMBL23805266 0.80 HTR2A (0.55) HTR2AHTR2CHTR2BCDK2HTR6
Hydrochloric Acid SCHEMBL23805267 0.80 HTR2A (0.62) HTR2AHTR2CHTR2BCDK2HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 US disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR2A 5/4885HTR2C 4/4885HTR2B 2/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR2A 377/4885HTR2C 1196/4885HTR2B 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.